RTPDMDG Meetings

Douglas M. Sheeley, D. Sc.
Division of Biomedical Technology, National Institutes of Health

Michael B. Fessler, M.D.
National Institute of Environmental Health Sciences

Christie L. Hunter, PH.D.
Applied Biosystems

Tetsuya Terasaki, PH.D.
Tohoku University

Dr. Scott D. Patterson
Amgen, Inc.

Date	Seminar Title	Speaker	Abstract
October 14, 1999 Inaugural Meeting	"Citrus Juices and Intestinal Barrier Function in Man: Not Pulp Fiction"	Dr. Paul Watkins University of North Carolina at Chapel Hill	Click Here
February 8, 2000	"Cytochrome P-450 and Other Drug Metabolizing Enzymes at the Change of the Millenium: What Have We Learned and What Else Do We Need to Know?"	Dr. Fred Guengerich Vanderbilt University	Click Here
May 8, 2000	"Pharmacogenetics: Drug Development and Surveillance Do We Keep Score of ADR's or Do Something About It?"	Dr. Penny Manasco Glaxo Wellcome	Click Here
October 4, 2000	"Physiologically Based Pharmacokinetic Modeling in Pharmaceutical Safety Assessment: An Example with Retinoic Acid and Cross-Species Extrapolation of Metabolism and Teratogenicity"	Dr. Harvey Clewell ICF Consulting	Click Here
February 13, 2001	"CYP3A4: Implications for Drug Development and Toxicology"	Dr. Steven A. Wrighton Eli Lilly	Click Here
May 15, 2001	"Genetic approaches to study metabolism and transport"	Dr. Erin Schuetz St. Jude Children’s Research Hospital	Click Here
November 7, 2001	"Covalent Binding in Drug Discovery and Development: A Pragmatic View of the Issue of Reactive Intermediates"	Dr. Thomas A. Baillie Department of Drug Metabolism, Merck Research Laboratories	Click Here
February 5, 2002	"Functional Implications of Genetic Variation in the Human Cytosolic Sulfotransferases"	Dr. Rebecca Blanchard Raftogianis Fox Chase Cancer Center	Click Here
May 1, 2002	SYMPOSIUM: Nuclear Imaging	Dr. Joanna Fowler Brookhaven National Laboratory Dr. Timothy DeGrado Duke University Dr. Jerry Collins Food and Drug Administration	not available
October 9, 2002	"Structural Studies of Drug Metabolizing P450s: Deciphering Their Catalytic Diversity"	Dr. Eric F. Johnson The Scripps Research Institute	Click Here
March 5, 2003	SYMPOSIUM: Herbal Drugs	Dr. Nicholas Oberlies RTI International Dr. Thomas Walle Medical University of South Carolina Dr. John Cardellina National Cancer Institute Joe Graedon, M.S. and Dr. Teresa Graedon The People’s Pharmacy	not available
May 28, 2003	"Genetic variabilities in CYP3A and P-glycoprotein - are they clinically important?"	Dr. Grant R. Wilkinson Vanderbilt University	not available
September 25, 2003	"The Challenges of Designing Prodrugs of Opioid Peptides that Permeate the Intestinal Mucosa and the Blood Brain Barrier"	Dr. Ronald T. Borchardt University of Kansas at Lawrence	not available
February 24, 2004	SYMPOSIUM: Drug Transporters	Dr. Joseph W. Polli GlaxoSmithKline Dr. Leslie Z. Benet University of California at San Francisco Dr. Kim L. R. Brouwer University of North Carolina at Chapel Hill Dr. David S. Miller National Institutes of Environmental Health Sciences Dr. Gordon L. Amidon University of Michigan	not available
May 19, 2004	"Can defective genes be good for you? Smoking, Cancer, and CYP2A6"	Dr. Rachel F. Tyndale University of Toronto	not available
September 22, 2004	Noninvasive Assessment of CYP3A Activity "The Eye as a Window on Drug Metabolism"	Dr. Evan D. Kharasch University of Washington	not available
2004-2006 to be updated soon

May 18, 2006	"Is There an Impact of CYP3A5 Expression on CYP3A-mediated Drug Interactions?"	Dr. Steve Hall Indiana University	Click here
November 14, 2006	"Current Issues with Drug Metabolism in Drug Development"	Dr. Gerald Miwa Millennium Pharmaceuticals	Click here
March 1, 2007	SYMPOSIUM: Drug-Drug Interactions	Dr. Brain Houston University of Manchester Dr. Punit Marathe Bristol-Myers-Squibb Dr. Marrilyn Morris The State University of New York Dr. Soraya Madani Novartis Pharmaceutical Corporation Dr. John Murphy University of Arizona	Click here
October 17, 2007	Challenges Posed by a New Draft FDA Guidance on the Safety Assessment of Drug Metabolites	Dr. Clay B. Frederick Merck & Co., Inc.	Click here
December 6, 2007	Pharmacogenomics: Science and Translation	Dr. Richard M. Weinshilboum Mayo Clinic College of Medicine	Click here
March 5, 2008	WINTER SYMPOSIUM Quantitative Proteomics and Its Application to ADME	Douglas M. Sheeley, D. Sc. Division of Biomedical Technology, National Institutes of Health Michael B. Fessler, M.D. National Institute of Environmental Health Sciences Christie L. Hunter, PH.D. Applied Biosystems Tetsuya Terasaki, PH.D. Tohoku University Dr. Scott D. Patterson Amgen, Inc.	Patterson -Click here
May 21, 2008	Impact of Infection and Inflammation on Drug Metabolizing Enzymes and Pharmacokinetics	Dr. Edward Morgan Emory University	not available