Previous Meetings


Date
Seminar Title
Speaker
Abstract/Slides
October 6th, 2011ADME in NAFLD: Increased Risk of Adverse Drug ReactionsNathan Cherrington, Ph.D
May 26th, 2011The Basis for the Clinical Interaction Between Clopidogrel and Proton Pump Inhibitors (PPIs)Andrew Parkinson, Ph.DClick Here
March 17th 2011Symposium :
Drug Transporters: What's All the Flux about?
Joseph W. Polli, Ph.D

Thomas J. Raub, Ph.D

Raymond Evers, Ph.D

Aleksandra Galetin, Ph.D

Alex Sparreboon, Ph.D

Summer 2010

Ethnicity and Global Drug Development: Focus on Asia


Bob Powell, Ph.D




March 4th, 2010



SYMPOSIUM:  Drug-Drug Interactions
Haig Bozigian, Ph.D

Steve Castellino, Ph.D

Chris Kemper, Ph.D

Michael Devito, Ph.D

Paul Watkins, MD
Click Here





Click here

Click here
December 10, 2009Role of Transporter in the Blood-Brain Barrier in the CNS
Distribution of Drugs:  In Vitro – In Vivo Correlation

William F. Elmquist, Pharm.D., Ph.D:
Professor of Department of Pharmaceutics,
School of Pharmacy, University of Minnesota, Minneapolis, MN

Click here


December 10, 2009

Medicinal Chemical Strategies to Reduce Transporter-Mediated Efflux for Delivery of Xenobiotics Across the Blood-Brain Barrier

Robert T. Jacobs, Ph.D:
Director of Chemistry, SCYNEXIS, Inc.





September 17, 2009

Blood, Bone, and Biology: Pharmacokinetics and the Discovery of Human Biotherapeutics

Paul G. Pearson, Ph.D.,
President and CEO, Pearson Pharma Partners




March 5, 2008Quantitative Proteomics and Its Application to ADME

Dr. Scott D. Patterson
Senior Director, Medical Sciences
Amgen, Inc.
Clinical Applications of Quantitative Proteomics




December 6, 2007Pharmacogenomics:  Science and TranslationDr. Richard M. Weinshilboum
Mayo Clinic College of Medicine



October 17, 2007



"Challenges Posed by a New Draft FDA Guidance on the Safety Assessment of Drug Metabolites"

Dr. Clay B. Frederick  
Merck & Co., Inc.

Click here







March 1, 2007







SYMPOSIUM:  Drug-Drug Interactions

Dr. Brian Houston
University of Manchester

Dr. Punit Marathe
Bristol-Myers-Squibb

Dr. Marrilyn Morris
The State University of New York

Dr. Soraya Madani
Novartis Pharmaceutical Corporation

Dr. John Murphy
University of Arizona









November 14, 2006
"Current Issues with Drug Metabolism in Drug Development"

Dr. Gerald Miwa

Millennium Pharmaceuticals


May 18, 2006
"Is There an Impact of CYP3A5 Expression on CYP3A-mediated Drug Interactions?"
Dr. Steve Hall
Indiana University

September 22, 2004
Noninvasive Assessment of CYP3A Activity
"The Eye as a Window on Drug Metabolism"

Dr. Evan D. Kharasch

University of Washington

May 19, 2004
"Can defective genes be good for you?
Smoking, Cancer, and CYP2A6"
Dr. Rachel F. Tyndale
University of Toronto

February 24, 2004
SYMPOSIUM: Drug Transporters
Dr. Joseph W. Polli
GlaxoSmithKline

Dr. Leslie Z. Benet
University of California at San Francisco

Dr. Kim L. R. Brouwer
University of North Carolina at Chapel Hill

Dr. David S. Miller
National Institutes of Environmental Health Sciences

Dr. Gordon L. Amidon
University of Michigan


September 25, 2003
"The Challenges of Designing Prodrugs of Opioid Peptides that Permeate the Intestinal Mucosa and the Blood Brain Barrier"
Dr. Ronald T. Borchardt  
University of Kansas at Lawrence

May 28, 2003
"Genetic variabilities in CYP3A and
P-glycoprotein - are they clinically important?"
Dr. Grant R. Wilkinson
Vanderbilt University




March 5, 2003


 

SYMPOSIUM: Herbal Drugs
Dr. Nicholas Oberlies
RTI International

Dr. Thomas Walle 
Medical University of South Carolina

Dr. John Cardellina
National Cancer Institute

Joe Graedon, M.S. and Dr. Teresa Graedon
The People’s Pharmacy

October 9, 2002
"Structural Studies of Drug Metabolizing P450s: Deciphering Their Catalytic Diversity"
Dr. Eric F. Johnson
The Scripps Research Institute

May 1, 2002
SYMPOSIUM: Nuclear Imaging
Dr. Joanna Fowler
Brookhaven National Laboratory

Dr. Timothy DeGrado
Duke University

Dr. Jerry Collins
Food and Drug Administration


February 5, 2002
"Functional Implications of Genetic Variation in the Human Cytosolic Sulfotransferases"
Dr. Rebecca Blanchard Raftogianis
Fox Chase Cancer Center
Click Here
November 7, 2001
"Covalent Binding in Drug Discovery and Development: 
A Pragmatic View of the Issue of Reactive Intermediates"
Dr. Thomas A. Baillie
Department of Drug Metabolism, Merck Research Laboratories
Click Here
May 15, 2001"Genetic approaches to study metabolism and transport"Dr. Erin Schuetz
St. Jude Children’s Research Hospital
Click Here
February 13, 2001
"CYP3A4:  Implications for Drug Development and Toxicology" 
Dr. Steven A. Wrighton
Eli Lilly 
Click Here
October 4, 2000
"Physiologically Based Pharmacokinetic Modeling in Pharmaceutical Safety Assessment: An
 Example with Retinoic Acid and Cross-Species Extrapolation of Metabolism and Teratogenicity"
Dr. Harvey Clewell
ICF Consulting
Click Here
May 8, 2000
"Pharmacogenetics: Drug Development and Surveillance
Do We Keep Score of ADR's or Do Something About It?"
Dr. Penny Manasco
Glaxo Wellcome
Click Here
February 8, 2000
"Cytochrome P-450 and Other Drug Metabolizing Enzymes at the Change of the Millenium: What Have We Learned and What Else Do We Need to Know?"
Dr. Fred Guengerich
Vanderbilt University
Click Here
October 14, 1999
Inaugural Meeting

"Citrus Juices and Intestinal Barrier Function in Man: Not Pulp Fiction"

Dr. Paul Watkins
University of North Carolina at Chapel Hill
Click Here







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